Seasonal variations and the risk of venous thromboembolism: A narrative review article

Ali Soleimany,Reza Hajizadeh,Hanieh Sakha,Sahar Ghodratizadeh

doi:10.15171/jarcm.2019.020

Abstract

Different investigations on seasonal variations of the pulmonary thromboembolism and deep vein thrombosis (DVT) incidence have not yielded a definite conclusion. Some papers showed significant increase in incidence of thromboembolism in winter; on the other hand, others neglected that correlation. Some articles have tried to show infrastructure of these variations. Better understanding of the cornerstone of these variations can result in prevention of disease and saving lives of susceptible people. In this narrative review article, we reviewed previous articles according to the region of study and tried to find the factors affecting diverse results among different studies.

Highlights

Different investigations on seasonal variations of the incidence of pulmonary thromboembolism and deep vein thrombosis (DVT) have not yielded a definite conclusion
The temperature and humidity are different in Asia and Europe
The ISI Web of Knowledge, PubMed, Scopus, EBSCO, and IranMedex databases were searched for articles with keywords related to season, venous thromboembolism (VTE), pulmonary embolism (PE), and DVT

Summary

Introduction

Different investigations on seasonal variations of the incidence of pulmonary thromboembolism and deep vein thrombosis (DVT) have not yielded a definite conclusion. Different methodology, and geographic and genetic confounders can explain part of this heterogeneity.[1] A new study showed that in old persons, seasonal variation was an independent risk factor for venous thromboembolism (VTE).[2] Some studies showed that predisposing genetic risk factors were different among Asian and European populations.[3] the temperature and humidity are different in Asia and Europe. We decided to investigate the results of different studies about seasonal variation of VTE in Asian and European countries.

Results

Conclusion