Abstract
1. 1. Sarcoplasmic reticulum (SR) isolated from the hearts of hibernating Richardson's ground squirrels was found to have the highest rate of calcium uptake when compared to SR isolated from spring, fall and winter active animals between 37.4°C. 2. 2. Spring and winter animals had the lowest rates of calcium uptake, with the Arrhenius plots being almost superimposable over most of the temperature range, while fall animals showed an intermediate uptake rate in between the hibernating and winter active animals. 3. 3. These results indicate that biochemical changes occur in the SR as the animal prepares for hibernation, and that a high rate of SR calcium uptake is characteristic of ground squirrels in hibernation.
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