Abstract
Pharmacognostical standardization and toxicity profile of the methanolic leaf extract of Plectranthus amboinicus (Lour) SprengPreeja G. Pillai, P. Suresh, Gayatri Aggarwal, Gaurav Doshi, Vidhi Bhatia
Highlights
Marine Ecosystem remains the habitat of organisms from various phyla amidst which fishes are the most diversified group
The toxicity was evaluated by mouse bioassay using Swiss Albino mice which is expressed in mouse units (MU/g)
The present study proved that T. oblongus is highly toxic and consumption of the same can pose serious dangers of health hazards and possibility of lethality to humans
Summary
Marine Ecosystem remains the habitat of organisms from various phyla amidst which fishes are the most diversified group. Several toxic marine organisms are reported till date and fishes have exhibited toxicity at extremities. The coastline of the Bay of Bengal and Arabian Sea continues to be a rich fishing ground in the South Asian region and India is one of the world’s largest marine natural products’ nations. The south east coast of India extends its coastal waters from the state of Tamil Nadu to Odisha. Among the wide varieties of fishes found in these waters, the pufferfishes form reasonable quantities. Pufferfishes produce a potent neurotoxin named Tetrodotoxin (TTX) which is a sodium channel blocker in cell membranes. Reports indicated that TTX is much similar to saxitoxin (STX), which causes paralytic shellfish poisoning (How et al, 2003)
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