Abstract
The toxic role of heavy metals in lakes, rivers and marine ecosystems has been very often investigated during recent years. The toxicity of the individual metals and their ability to promote various metabolic changes of fish organisms are detected. It has been suggested that heavy metal ions stimulate lipid peroxidation and O{sub 2}{sup {minus}}-dependent formation of OH free radicals. An important aspect of free radical-mediated toxicity is that it is moderated by several cellular defense mechanisms including enzymatic and non-enzymatic systems. The aim of present work was to investigate the effect of seasonal variations of erythrocyte SOD, lipid peroxidation (LP) as well as water heavy metals and environmental conditions on bream fishes from two different lakes.
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