Abstract

1. 1. In the active, normothermic, male ground squirrel ( Citellus citellus) phenylethanolamine-N-methyl transferase (PNMT) and monoamine oxidase (MAO) activity was studied during different seasons: in September, February and April. 2. 2. The adrenal weight and PNMT activity (counts/min per pair of adrenals) were significantly higher in animals kept at a room temperature of 20–25°C and examined in early spring (April) than in those kept at the same room temperature but examined in autumn, before the period of hibernation (September). 3. 3. MAO activity (counts/min per mg) in the liver, heart, kidney and hypothalamus was significantly lower in animals examined in April compared with those examined in September. 4. 4. In animals kept at a room temperature of 30°C (so that hibernation could be prevented) and examined in February the adrenal weight and PNMT activity were significantly higher when compared with animals examined in autumn. MAO activity in the liver, heart, kidney and hypothalamus of these animals was significantly lower than in those examined in September.

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