Seasonal Changes in Kidney Function in CKD of Uncertain Etiology

Abstract

Chronic kidney disease of uncertain etiology (CKDu) is a term used to describe kidney disease without traditional risk factors.1 Disease clustering is reported from Central America, corresponding with the warmest areas along the Pacific coast and Srilanka.2 The Indian CKD registry reported CKDu as the second common cause of CKD in India, accounting for 16% of cases.3 We have described a new CKDu hotspot, Tondaimandalam nephropathy, from the northern coastal districts of Tamil Nadu, India.4 The other CKDu hotspots from India include the Uddhanam, Andhra Pradesh, and Narsinghpur and Badamba blocks of Odisha.