Abstract

The annual cycle of the interrenal tissue in male common frogs, Rana temporaria, has been studied. From the changes in nuclear and cellular area, lipid and cholesterol content and mitotic activity it has been concluded that: 1. After a short resting phase in mid-winter the interrenal tissue shows a high secretory activity which reaches its maximum at the end of the breeding season. 2. After breeding secretion and production decrease to a minimum in mid-summer. 3. A restoration follows from late summer till early winter. During this period secretory activity is accompanied by a relatively high production.

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