Abstract
Hybrid mice shed new light on the interactions between regions of the genome that help drive the evolution of new species by reducing the fertility of hybrid males.
Highlights
Not all of the genetic differences between recently separated species contribute to reproductive isolation, and identifying the ones that do has been a major challenge
Relatively few genes that contribute to reproductive isolation have been found, and most of them come from the fruit fly Drosophila (Presgraves, 2010)
Reproductive isolation is not a simple trait that is caused by a few genes: it is due to the contributions of many genes throughout the genome (e.g., White et al, 2011)
Summary
Not all of the genetic differences between recently separated species contribute to reproductive isolation, and identifying the ones that do has been a major challenge. Relatively few genes that contribute to reproductive isolation have been found, and most of them come from the fruit fly Drosophila (Presgraves, 2010). In eLife, Leslie Turner and Bettina Harr of the Max Planck Institute of Evolutionary Biology report that they have developed a new approach to study reproductive isolation in house mice (Turner and Harr, 2014).
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