Abstract
Abstract The activation step of biotin into biotinyl-AMP, which precedes the fixation of the prosthetic group on the apocarboxylases, has been examined in cultured fibroblasts from patients with biotin-dependent multiple carboxylase deficiencies. Two kinds of patients were tested, those with a defective holocarboxylase synthetase activity and those with a low level of the vitamin in the plasma. In both cases, the activation step of biotin was found to be very close to normal values.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
