Abstract

On the basis of proteomics, modern data on the features of bone remodeling in astronauts after long-term space flights are presented. We describe the regulatory proteins of the blood proteome that are significantly associated with bone remodeling processes. By analyzing large amounts of data, we for the first time determined associations of signaling proteins that are process regulators characterizing new steps of bone remodeling in astronauts during the acute period of readaptation after landing.

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