Abstract
Larvae are a diverse set of postembryonic life forms distinct from juveniles or adults that have evolved in many animal phyla. Echinoids (sea urchins and sand dollars) generate rapidly developing, morphologically simple, and optically transparent larvae and are a well-established model system supported by a broad array of genomic resources, experimental approaches, and imaging techniques. As such, they provide a unique opportunity to study postembryonic processes such as endocrine signaling, immunity, host-microbe interactions, and regeneration. Here we review a broad array of literature focusing on these important processes in sea urchin larvae, providing support for the claim that they represent excellent experimental study systems. Specifically, there is strong evidence emerging that endocrine signaling, immunity, and host-microbe interactions play major roles in larval development and physiology. Future research should take advantage of sea urchin larvae as a model to study these processes in more detail.
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