Sea Buckthorn Seed Powder Provides Protection in the Oxidative Stress Produced by Thermally Oxidized Sunflower Oil in Rabbits

Abstract

SBT seed powder was used against the oxidative stress produced by thermally oxidized sunflower oil. OSFO and SBT powder were orally administered to the rabbits. Blood biochemistry, hematology and liver pathology were investigated. The results show that OSFO produce changes in the blood biochemistry and hematology and alterations in the liver. However, the toxicity of OSFO was minimized when rabbits were fed with SBT seed powder. The SBT seed both in independent and in fortified forms significantly decreases the serum cholesterol, LDL-c, ALT (alanine aminotransferase) and TG values, whereas it increases serum glucose and HDL-c values. The seed powder normalizes all the hematological indices. Histopathological investigation of the liver reveals that OSFO intake causes severe adverse changes, whereas SBT seed powder was found to restore the normal condition. It was concluded that SBT seed powder has strong potential to reduce the toxicity of oxidized lipids in model animals. Practical Applications Thermally oxidized edible oils are one of the main concerns of the modern-day food chemists and technologists. The ingestion of these oxidized lipids results into the toxic effects on human beings. This study clearly showed for the first time that SBT seed powder reduces the degenerative and toxic changes in the liver produced by thermally oxidized lipids. It has been found that SBT seed powder supplementation has protective effects against the toxicity of OSFO by increasing the antioxidant potential.