Screening of Autism Spectrum Disorder in Metabolic Disorders by M-CHAT R/F

Abstract

Abstract Background no exact cause can be defined for autism spectrum disorder (ASD) but, recent studies proved a great association between the presence of ASD symptoms and different metabolic disorders which provides a great consideration in diagnosis and treatment of children with ASD. Aim of the Work is to detect the prevalence of ASD among children with metabolic disorders using M-CHAT-R/F as a screening tool. Patients and Methods An analytical (observational) cross sectional research design. The subjects of this study comprised a convenient sample of 100 children diagnosed as having Metabolic Disorders with age range between (16-30) months. The validated Arabic version of Modified Checklist of Autism- Revised and Follow up (M-CHAT R/F) was applied for all children. Results screening of 100 children with unequal distribution among 13 types of metabolic disorders for ASD by use of M-CHAT-R/F found 22% had low risk (safe), 58% had moderate risk and 20% had high risk. Conclusion children with metabolic disorders are at a high risk for ASD. Early detection of these cases provides early intervention and better outcome.