Screening of Antifungal Activity of Ganoderma Lucidum extract Against Medically Important Fungi

Abstract

Antimicrobials of plant origin are effective in the treatment of infectious disease while simultaneously mitigating many side effects that are often associated with synthetic antimicrobials. In the present study crude aqueous and ethanolic extract of Ganoderma lucidum was evaluated for its antifungal activity against the clinically important fungi namely Candida albicans, Aspergillus niger, Penicillium marneffei, Cryptococcus neoformans, Trichophyton rubrum, and Microsporum canis. The result showed ethanolic had high inhibitory action against the studies fungus when compared to aqueous extract. In both ethanolic and aqueous extract the maximum inhibition activity was observed against Candida albicans followed by Trichophyton rubrum, Microsporum canis, Aspergillus niger, Penicillium marneffei and Cryptococcus neoformans.