Abstract
Comparative analysis of three screening methods (MS2, Chemstrip LN, and Gram's stain) was performed on 386 urine specimens collected from a Veterans Administration Medical Center Hospital patient population. The prevalence rate of urinary tract infections (UTIs) was 25%. The negative predictability of UTIs was comparable with all three methodologies at the ≥ colony-forming units (CFU) per milliliter level but was lowest at the 104 CFU mL level with the Chemstrip LN. We concluded that the MS2 screening procedure served this population best in terms of microbiologist time and predictability. Clinical preselection of subgroups at high risk for UTI is necessary in order to adequately process low-colony count (≤103 CFU/mL) urine specimens. Lowering the threshold for detection of urine screening tests would negate the value of these methods.
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