Abstract
Letters1 June 1993Screening for Renovascular HypertensionSamuel J. Mann, MD and Thomas G. Pickering, MDSamuel J. Mann, MDSearch for more papers by this author and Thomas G. Pickering, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-11-199306010-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Two of our previous studies [1, 2] relate to Dr. Ruttimann and colleagues' interesting suggestion that smokers have a higher baseline renin value and an increased renin reactivity to captopril. First, we showed that smokers (also defined as persons who smoke 20 or more cigarettes per day) who are matched to nonsmokers for age, gender, and race had the same plasma renin activity values as nonsmokers [1]. In our recent second study, we showed that the bulk of false-positive captopril tests arise in patients whose baseline plasma renin activity value is elevated [2]. In contrast, among patients with ...
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