Abstract
The decline of the incidence of stomach cancer in western countries is a well-known phenomenon [1]. Nevertheless, in 1985, it was still the second most common cancer in the world, and the most common cancer in developing countries [2]. Symptoms are rather non-specific, so most cases are diagnosed when the tumor has already invaded the muscular layer. The prognosis is then very poor: five-year relative survival was 18% for all incident cases in the U.S.A. around 1987 [3], and it was 19% in Europe around 1984 [4]. In contrast, survival is extremely good for early cancers: in the Japanese series, the five-year relative survival is 98% [5], and in the U.S.A. it is 70% [6].
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