Abstract

BackgroundStroke is a disease which occurs when the blood supply to the brain is interrupted, depriving brain tissue of oxygen, resulting in cell death. The symptoms of stroke include: numbness, paraplegia, dysarthria, ataxia, etc. The most common complication is infection. The highest death rates among hospitalized stroke patients are from pneumonia.ObjectiveTo develop a score for predicting post-stroke pneumonia infection and identify risk factors for patients with post-stroke pneumonia.Study designRetrospective case-control.SettingUttaradit hospital (the tertiary hospital), Thailand.MethodA retrospective data study was conducted at Uttaradit hospital, Thailand from January 2014 to October 2018 in which all of the subjects were diagnosed with either stroke with pneumonia or without pneumonia by a physician. The selected 324 stroke patients were divided into two groups: 108 patients were stroke with pneumonia and 216 patients were stroke without pneumonia. This study involved data collection and analysis of study characteristics to develop a predictive score for post-stroke pneumonia.ResultsThis study identified risk factors and developed a score for predicting post-stroke pneumonia infection by using significant covariates (duration of admission; 1–10 days=0 points, 11–20 days=1 point, more than 20 days=2.5 points, Cardiovascular disease=1.5 points, Nasogastric tube=2 points, Urinary tract infection=1 point). This score was interpreted to three groups; low risk (<2 points), moderate risk (2.5–4 points), and high risk (>4 points). Sensitivity was 80.56% and specificity was 93.52%.ConclusionA simple prediction tool was developed that uses only four clinical variables to predict risk of post-stroke pneumonia with high sensitivity and specificity.

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