Abstract
The effects of scopolamine and methylscopolamine (0.125—1.0 mg/kg) on play fighting by juvenile rats were compared. At doses of 0.25 mg/kg or higher, the centrally active anticholinergic, scopolamine hydrobromide, depressed pinning and reduced the total duration of play fighting. In contrast, scopolamine methylbromide had no effect. Neither drug reliably affected social investigation or rearing.
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