Abstract

Sclerotic lesions of the jaw are uncommon but may be clinically relevant. In this pictorial review, the most common sclerotic lesions are discussed. Three categories of lesions are distinguished; odontogenic sclerotic lesions, non-odontogenic sclerotic lesions, and mixed lytic-sclerotic lesions. In each group, non-neoplastic conditions are discussed first, followed by benign and malignant neoplasms. For each disease a brief overview is given, including histological features, epidemiology, symptoms, typical location, imaging features, and treatment. This review emphasizes which basic observations are essential to the evaluation of sclerotic jaw lesions and what elements have to be taken into account to create a proper differential diagnosis.

Highlights

  • Sclerotic jaw lesions are not rare and are frequently encountered on radiographs and computed tomography (CT)

  • When a sclerotic lesion is observed in the jaw, attention should first be focused on whether and how the lesion is related to a tooth [1,2,3,4,5]

  • If a lesion is intimately associated with a tooth, the lesion is most likely odontogenic, and the number of possible diagnoses is limited

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Summary

Introduction

Sclerotic jaw lesions are not rare and are frequently encountered on radiographs and computed tomography (CT). It represents a group of benign lesions of unknown etiology characterized by the substitution of normal bone by fibrous tissue with newly formed mineralized structures [6, 7]. Periapical COD is seen adjacent to a tooth-bearing area associated with one or more vital mandibular anterior teeth (Figure 1a, b).

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