Abstract

ObjectiveTo test whether inhibition of sclerostin by a targeted monoclonal antibody (Scl-Ab) protects from bone and cartilage damage in inflammatory arthritis. Sclerostin is a potent inhibitor of bone formation and...

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Similar Papers

Paper Title
Journal
Date
Author
Zoledronic acid protects from local and systemic bone loss in tumor necrosis factor-mediated arthritis
K Redlich ... P Herrak
Arthritis Research & Therapy | VOL. 6
K Redlich, et. al.K Redlich ... P Herrak
01 Jan 2004
Plasma cells promote osteoclastogenesis and periarticular bone loss in autoimmune arthritis.
Hiroshi Takayanagi ... George Kollias
The Journal of clinical investigation | VOL. 131
Hiroshi Takayanagi, et. al.Hiroshi Takayanagi ... George Kollias
15 Mar 2021
RANKL is a Marker and Mediator of Local and Systemic Bone Loss in Two Rat Models of Inflammatory Arthritis
Marina Stolina ... Paul J Kostenuik
Journal of Bone and Mineral Research | VOL. 20
Marina Stolina, et. al.Marina Stolina ... Paul J Kostenuik
01 Oct 2005
AB0147 Role of Sclerostin in Rheumatoid Arthritis: New Insights
S.E Ibrahim ... N Farouk
Annals of the Rheumatic Diseases | VOL. 73
S.E Ibrahim, et. al.S.E Ibrahim ... N Farouk
01 Jun 2014
View more papers

More From: Annals of the Rheumatic Diseases

Paper Title
Journal
Date
Author
Single-cell transcriptomes and chromatin accessibility of endothelial cells unravel transcription factors associated with dysregulated angiogenesis in systemic sclerosis
Mengqi Huang ... Robert Lafyatis
Annals of the Rheumatic Diseases | VOL. -
Mengqi Huang, et. al.Mengqi Huang ... Robert Lafyatis
16 May 2024
Remission and low disease activity are associated with lower healthcare costs: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort
Megan R W Barber ... Ann E Clarke
Annals of the Rheumatic Diseases | VOL. -
Megan R W Barber, et. al.Megan R W Barber ... Ann E Clarke
16 May 2024
Treatment of recalcitrant psoriasis and psoriatic arthritis with a combination of a biologic plus an oral JAK or TYK2 inhibitor: a case series
M Grace Hren ... Saakshi Khattri
Annals of the Rheumatic Diseases | VOL. -
M Grace Hren, et. al.M Grace Hren ... Saakshi Khattri
16 May 2024
News from EULAR
Yuliia Caliskan
Annals of the Rheumatic Diseases | VOL. 83
Yuliia CaliskanYuliia Caliskan
15 May 2024
View more papers