Abstract
Sclerosing polycystic adenosis is a rare benign salivary gland lesion that more commonly involves the parotid. A 65-year-old male patient, without systemic changes, presented swelling in the lower lip for 18 months. Clinical examination revealed a painless submucosal nodule in the lower labial mucosa with a 5-mm diameter. The diagnostic hypotheses were mucocele and hyperplastic minor salivary gland, and total surgical excision was performed. Histopathologic examination showed a well-circumscribed lobular proliferation of ectatic ductal structures with cystic dilatation and periductal sclerosis. The ductal spaces were lined by flattened to cuboidal epithelium containing squamous and apocrine-like metaplasia and occasional mucin. The perilesional region showed minor salivary glands with an infiltration area along with focal lymphoplasmacytic inflammatory infiltrate. The final diagnosis of sclerosing polycystic adenosis was made based on clinical and histopathologic examination. The patient has been followed up for 6 months and is currently free of the lesion.
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