Abstract
Sclerosing polycystic adenosis (SPA) was first described in 1996. 1 The most common site is the parotid, but SPA may occur in the submandibular and minor glands. SPA in the sinonasal tract has been published. The reported age spectrum is 9–84 years. Rare cases associated with other lesions are on record. Cases with multifocality have been documented. SPA with a familial occurrence has been reported. Histologically, SPA is a sharply circumscribed, unencapsulated with acinar and ductal components. Cells show variable cytomorphology; foamy-vacuolated (sebocyte-like), apocrine, mucous, clear/ballooned, squamous and oncocyte-like features. In most cases, a cystic component is present. Cysts may be few. 2 The stroma is sclerotic, rarely myxoid, variably inflamed and frequently contains fat. SPA frequently (50%) harbors intraductal epithelial proliferations. These have often been labeled as dysplastic-ductal carcinoma in situ (DCIS). The frequency of high-grade DCIS is
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