Sclerosing Angiomatoid Nodular Transformation (SANT) Involving Spleen: A Case Report

Abstract

Background: Sclerosing angiomatoid nodular transformation (SANT) also known as multinodular haemangioma is a recently recognized, rare non-neoplastic vascular sclerosing mass-like lesion of the spleen with uncertain etiology, presents most commonly as an asymptomatic splenic mass found incidentally on imaging studies but may cause abdominal pain or discomfort, leading to splenectomy, as the risk of rupture and malignancy cannot securely be ruled out. Diagnosis is made postoperatively on histology. Case report: We report a case of 64-years old man, with incidentally detected splenic lesion on imaging who underwent elective splenectomy and was diagnosed postoperatively on histological examination. The post-operative course was uneventful and the patient was discharged on POD9. Conclusion: SANT of the spleen although rare, is to be considered as a differential diagnosis of splenic vascular lesions. Further research should focus on clinical and radiological characteristics and consideration of observation with serial imaging as an alternative approach. Open or laparoscopic splenectomy is still known to be curative as it is both therapeutic and diagnostic.