Abstract

People living in developed countries are exposed to over 100 000 chemically pure, man-made substances (and an immense number of their combinations). 98% of these chemicals have never been tested for their effects on our health or environment. Traditional toxicity testing in animal models has proven unreliable. With the help of concepts, methods and tools developed in modern biology, scientific toxicity assessment is at present possible. Various fields of toxicology are reviewed and the scientific methods allowing their reliable assessments are summarized. The implementation of scientific toxicity testing is expected to save yearly millions of lives in developed countries.

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