Scientific Opinion on the safety and efficacy of Coxiril® (diclazuril) as a feed additive for turkeys for fattening

Abstract

Coxiril®, containing 0.5 % diclazuril, is intended for the control of coccidiosis in turkeys for fattening at concentrations between 0.8 and 1.2 mg diclazuril/kg complete feed. The highest proposed use level (1.2 mg diclazuril/kg feed) is considered safe for turkeys for fattening. Diclazuril has no substantial antibacterial activity. Diclazuril from Coxiril® is considered toxicologically equivalent to the other currently authorised diclazuril. The use of Coxiril® at the highest proposed use level of 1.2 mg diclazuril/kg complete feed in turkeys for fattening is safe for the consumer since Maximum Residue Limits are not exceeded. Coxiril® is considered non-irritant to eyes and skin. It is not a potential skin sensitiser. User exposure to Coxiril®, as a result of normal handling, is unlikely to cause respiratory or systemic toxicity. Based on a Phase I assessment, the use of diclazuril in turkeys for fattening at the high use level does not pose a risk to the environment. Diclazuril from Coxiril® has the potential to control coccidiosis in turkeys for fattening at a minimum concentration of 0.8 mg/kg complete feed. This conclusion is derived from literature data, and from recent studies performed with Coxiril®.