Sci-Thur AM: Planning - 08: Validation of a commercial Monte Carlo code used for stereotactic radiosurgery and stereotactic body radiation therapy.

Abstract

Our project consisted of validating the BrainLab iPlan Monte Carlo algorithm, used in conjunction with the stereotactic radiosurgery (SRS) mode of the Varian Novalis TX linear accelerator, for clinical use. Our approach was to "benchmark" the iPlan algorithm by comparing dose distributions with those obtained using a BEAMnrc model of the Novalis SRS mode. The BEAMnrc model was obtained by modifying an existing accelerator model to include the SRS flattening filter and source characteristics of the Novalis TX, and by reprogramming a component module to model the high definition 120-leaf multi-leaf collimator. The free parameters of interleaf air gap and leaf density were adjusted by matching to interleaf leakage profiles measured with EBT2 film. The BEAMnrc model was used to perform comparisons of depth dose curves and planar distributions for fields in homogeneous and heterogeneous slab phantoms between both MC codes and film. The source parameters of electron beam energy, size and angular spread were determined to be 6.6 MeV, 0.7 mm and 0.8 mm (cross and in-plane), and 1.27°, respectively. Comparisons between iPlan and EGSnrc MC codes show agreement within 2% for PDD curves, and a high pass rate (>98%) on gamma analysis (3%/3mm) for planar distributions, when the scored quantity is dose to medium. Discrepancies between both MC codes and film measurements were seen near bone inhomogeneities, where the film trend agrees somewhat with iPlan MC reporting dose-to-water. Further work is being performed to understand these differences and how film is used to measure dose near bone.