Abstract
Multi-objective radiotherapy beam angle optimization is currently unavailable in commercial treatment planning software. The PARETO (Pareto-Aware Radiotherapy Evolutionary Treatment Optimization) software package presented here uses a sophisticated evolutionary algorithm that is capable of handling this difficult computational problem, while simultaneously incorporating IMRT fluence optimization. In this work, we focus on establishing the validity of the PARETO software in obtaining reasonable beam fluence maps for fixed gantry IMRT. PARETO IMRT solutions for a simple cylindrical phantom containing various structures (one planning target volume and one-to-three organs-at-risk) are compared to resulting fluence patterns at fixed beam angles generated by a commercial treatment planning system. We find that PARETO solutions agree well with those of the commercial system, with differences mainly attributable to the differences in the underlying dose calculation algorithm. Our approach to fluence modulation will allow PARETO to generate a database of optimal solutions for beam angles and IMRT plans that represent the best possible trade-offs between competing treatment objectives.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
