Abstract
The Polyglandular autoimmune syndromes (PGA) consists of immune dysfunction affecting two or more endocrine glands and other non-endocrine organs. There are PGA I, PGA II and PGA III. The second type involves dysfunction of the adrenal gland, namely Addison’s disease plus either autoimmune thyroiditis or type I Diabetes Mellitus. We report the case of a 21 year old female known to have Hashimoto disease who has presented with generalized fatigue and abdominal pain induced by an adrenal insufficiency onset. She was diagnosed with PGA II and treated with hydrocortisone and levothyroxine to which her condition quickly responded and eventually improved.
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