Abstract

About 40-70% of patients with pancreatic cancer experience severe pain. We recommend regional anesthetic procedures, especially the CT-guided neurolytic coeliac plexus block, in early pain states. If this is not sufficient pharmacological treatment according to the WHO guidelines should be used. When the dosage necessary for pain relief increases enormously (eg, 2 g morphine/day) we consider spinal opioids. For this reason we usually implant catheters and subcutaneous portsystems. The drug is then delivered percutaneously by portable external pumps. Using all possible and necessary methods for pain relief, we are successful in almost all patients with pancreatic cancer.

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