Abstract

Numerous studies show that people with schizophrenia live 1025 years less than the general population. The significant reduction in life expectancy is due to suicides, frequent comorbidity with heart and vascular diseases, metabolic disorders, including obesity and type 2 diabetes, as well as side effects of second-generation antipsychotics. Conditions for reducing the number of premature deaths in schizophrenia include changing the lifestyle of patients with improved nutrition and increased physical activity, increasing patient adherence to antipsychotic therapy with monitoring of the side effects of second-generation antipsychotics, as well as to the treatment of comorbid substance use disorders and comorbid somatic diseases.

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