Abstract
Relative radioactivity in prepenetration bodies, tails, and penetration gland secretions of carbon-14-labeled Schistosoma mansoni cercariae was determined. Labeled cercariae were obtained from previously infected Biomphalaria glabrata placed in a solution of d-glucose 14C. Radioactivity was also measured in schistosomules obtained from skin and lungs of mice infected with the labeled cercariae or after cercariae had penetrated a rat skin membrane. Approximately one-third of the total label was found in the tail. Sixty-nine percent of the label in the cercarial body had been lost after penetration of mouse tail skin and overnight incubation in Hank's saline. Penetration gland secretions accounted for 34–37% of the radioactivity of the cercarial body. Schistosomules recovered from mouse lungs 8 days after infection retained only 12% of the label detected in prepenetration cercarial bodies.
Published Version
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