Abstract
Schamberg's Disease (SD) also known as progressive pigmented purpuric dermatitis is the most common PPD (Pigmented Purpuric Dermatitis). PPD includes a spectrum of vascular diseases with an incidence of 0.18% of all skin and VD lesions. SD has Idiopathic aetiology, affects all races and ages (with mean age of 34 years). Males are affected more, especially the legs showing reddish brown purpuric patch/macules which has a chronic slow progression to other body parts. Long standing medications are thought to be one of the precipitating factor. Extravasation of RBCs from the superficial venous plexus of skin is thought to be the cause of skin discoloration. Histopapathology (HP) of the skin lesion show mild epithelial hyperplasia, occasional foci of spongiosis and lymphohistiocytic infiltrate with extravasation of RBCs. The disease has a cosmetic problem. No malignant transformation has been documented yet and to date there is no effective treatment. It is usually diagnosed by Clinical suspicion followed by HP confirmation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
