Abstract
Scanning electrochemical microscopy (SECM) is by no means the prominent analytical method used to study processes in living systems. SECM attracted a lot of attention toward studies in living systems due to its label-free, noninvasive ability over other analytical techniques. In addition to that is its applicability strength by providing high spatial and temporal resolution images. Due to its own characteristics, SECM has the ability to monitor the processes of living systems in real-time without harming the living system, which attracts SECM in a vast range of biological applications. The chapter discusses the use of SECM measurements in studies of both bacteria and eukarya domain living systems up to 2020. Also, it covers the use of different operational modes, different redox mediators, and different probes in SECM measurements to capture processes intracellularly, single-cell environment, and multiple cell environments of different living systems.
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