Abstract
Most cases of invasive cervical cancer arise in the developing world, where few resources exist for large-scale screening programs. Sankaranarayanan [1–5] has advanced visual inspection with acetic acid (VIA) as a method to screen women in low resource settings. While VIA has been extensively investigated, most studies rely on a gold standard of colposcopically directed biopsy. In our studies [6], the sensitivity of colposcopy is 96% and the specificity is 48% when discriminating between normal and abnormal cervical tissue.
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