Abstract
Studies of hair follicle development and scalp hair patterning in normal persons coupled with observations of aberrant scalp hair patterning in a variety of disorders of early brain and craniofacial development are indicative of the following hypothesis: Scalp hair patterning is determined at 10 to 16 weeks of fetal life and is secondary to the growth and shape of tissues which underlie the fetal skin, especially the brain. Thus aberrant scalp hair patterning may be utilized as a clinical indicator of aberrant growth and/or shape of the early fetal brain prior to 16 weeks' gestation.
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