Abstract

BackgroundNiger has one of the highest maternal mortality ratios in Sub Saharan Africa, of which postpartum hemorrhage is the leading cause. In 2014, Health and Development International and the Ministry of Health of Niger launched an initiative to introduce and scale-up three PPH interventions in health facilities nationwide: misoprostol, uterine balloon tamponade, and the non-pneumatic anti-shock garment.MethodsA two-phase mixed-methods evaluation was conducted to assess implementation of the initiative. Health facility assessments, provider interviews, and household surveys were conducted in May 2016 and November 2017.ResultsAll evaluation facilities received misoprostol prevention doses. However, shortages in misoprostol treatment doses, UBT kits, and NASG stock were documented. Health provider training increased while knowledge of each PPH intervention varied. Near-universal uterotonic coverage for PPH prevention and treatment was achieved and sustained throughout the evaluation period. Use of UBT and NASG to manage PPH was rare and differed by health facility type. Among community deliveries, fewer than 22% of women received misoprostol at antenatal care for self-administered prophylaxis. Among those who did, almost all reported taking the drugs for PPH prevention in each phase.ConclusionsThis study is the first external evaluation of a comprehensive PPH program taking misoprostol, UBT, and NASG to national scale in a low resource setting. Although gaps in service delivery were identified, results demonstrate the complexities of training, managing stock, and implementing system-wide interventions to reach women in varying contexts. The experience provides important lessons for other countries as they develop and expand evidence-based programs for PPH care.

Highlights

  • Niger has one of the highest maternal mortality ratios in Sub Saharan Africa, of which postpartum hemorrhage is the leading cause

  • 64% occurred in sub-Saharan Africa with Niger estimated to have one of the highest maternal mortality ratios in the region (553 maternal deaths per 100,000 live births)

  • Training and capacity The number of providers trained to implement the postpartum hemorrhage (PPH) Initiative increased over the evaluation period − 90% of the sample facilities had at least one provider trained in phase 1 while all facilities had a trained provider in phase 2

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Summary

Introduction

Niger has one of the highest maternal mortality ratios in Sub Saharan Africa, of which postpartum hemorrhage is the leading cause. 303,000 women died worldwide in 2015 from complications related to pregnancy and childbirth [1]. Of these deaths, 64% occurred in sub-Saharan Africa with Niger estimated to have one of the highest maternal mortality ratios in the region (553 maternal deaths per 100,000 live births). The primary cause of maternal mortality in Niger is postpartum hemorrhage (PPH), accounting for 29% of all maternal deaths [2]. Clinical protocols for childbirth in Niger require that prophylactic intra-muscular oxytocin be given to all women who deliver at health facilities. Misoprostol can be self-administered by women after delivery to help prevent PPH, and is safe to

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