Abstract

Abstract Disclosure: M. Esposito: None. V.G. Gonzalez: None. J. Pasqualotto: None. A. Morin: None. Introduction Transgender and gender diverse (TGD) people are those whose gender identity do not correspond with their sex assigned at birth. Gender identity law was approved in 2012, guarantees access to health care including hormones and surgical procedures reassignment without any requirement except "informed consent by the individual concerned". Last years the number of youth with TGD seeking gender affirming care has increased, resulting in the formation of multidisciplinary care teams to respond to the growing demand. Objective To characterize the population of transgender male(TM) attended in a Pediatric Endocrinology Service. Method Medical records of the Pediatric Endocrine Service were reviewed for youth with TGD seen from December 2017 to November 2022. Results We received 92 TGD individuals in our care team, of which 64 (69.6%) consulted in Endocrinology Service, 52 trans-male (TM) (81.3%) and 12 trans-female (TF) (18.7%). We describe TM group. Median age was calculated for first medical advice: 14 (9-16) years; self-perception TGD: 9 (3-14) years; and gender affirmation: 13 (6-16) years. Obesity and overweight was present in 22 (42.3%), normoweight in 25 (48%) and underweight in 5 (9.7%). Vitamin D levels (N: 35) were insufficient in 30 children (85.7%). At first visit 45 (86%) were in Tanner stage 5. Gonadotropin releasing hormone agonists (Gnrh) were used in 27 TM (51.9 %) to prevent the progression of biological puberty, median age at start of treatment was 14 (11-15) years. Testosterone (T) was used in 18 (34.6%) to develop sex characteristics of the self-identified gender, median age of beginning was 16 (14-17) years of which 12 have previously used GnRH. In 4 adolescents (7.7%) thoracic masculinization surgery was performed at a median age of 16 years. Conclusion Most of the TGD children and adolescents were TM with a median age at first visit of 14 years and tanner stage 5. Overweight and obesity rates were higher than international norms and are a common problem among TGD youth. They should be considered a high-risk group and targeted in obesity prevention and treatment efforts. The majority of transgender youth had vitamin D insufficiency, so we recommend sun exposure and physical activity. Although they consulted in the Pediatric Endocrinology Service, only 63.5% started some hormonal therapy. Gender affirmation require multidisciplinary approach in which endocrinologists play an important role. Presentation: Saturday, June 17, 2023

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