SAT-196 CAUSES, PROGRESSION, AND MAGNITUDE OF END-STAGE KIDNEY DISEASE OVER FOUR DECADES IN OMAN

Abstract

Oman is located in the in Southwest Asia, bordering the Arabian Sea, Gulf of Oman, and Persian Gulf, between Yemen and the United Arab Emirates (UAE). Ministry of Health plays a central role in the health status of the citizens and residents. Health data are collected routinely as a part of the mandatory requirement from all around the country including end-stage kidney disease (ESKD) data like the United States Renal Data System (USRDS). Continuous improvement in registries is required to improve capturing of ESKD patients for providing accurate data to health authorities and enhancing public awareness of the magnitude. Hereby, we examine the causes, progression, and magnitude of end-stage kidney disease (ESKD) over the last almost forty years in Oman. We examined ESKD data from 1983 to 2020. A questionnaire based on USRDS form 2728 is regularly completed by nephrologists once a citizen reached ESKD and then received by central office in Muscat, the capital city. The data entered are rechecked by 2 other team members. Data were analyzed using STATA software (Stata Corporation, College Station, TX). So far, a total of 5385 forms were completed, with a response rate of 92% (52.6% males). The mean (SD) age was 50.3 (14.0) years. By the 15th of October 2019, there were 4117 patients alive on renal replacement therapy (RRT); of whom 2040 were on hemodialysis (49.5%), 1860 were living with a functioning kidney transplant (45.1%), and 217 were receiving peritoneal dialysis (5.2%). The incidence of ESKD on RRT was 21, 75, 120, and 160 per million population in 1983, 2001, 2013, and 2019, respectively. Similarly, the prevalence of ESKD was 49, 916, 2386, and 4117 in 1983, 2001, 2013 and 2019, respectively. Among patients with ESKD on RRT, a progressive rise was seen in diabetic nephropathy, with 5.8%, 32.1%, 46% and 48% in 1983, 2001, 2013, and 2019, respectively. The number of citizens (incidence and prevalence) of ESKD has risen progressively over last four decades. The curtail of noncommunicable diseases is of vital importance to ameliorate the tsunami of ESKD in Oman. This is anticipated to continue at an even higher rate in view of the progressive rise in noncommunicable diseases. Hence, various stakeholders must combine effort to provide meaningful strategies towards various contributing factors.