SAT0192 Competitive elisa and bridging elisa with acid dissociation detect anti-drug antibodies in a greater proportion of patients treated with tnf-Αlpha inhibitors than classical bridging elisa

Abstract

Background:Therapeutic drug monitoring is used to guide treatment in patients treated with TNF-α inhibitors. Current bridging ELISA (bELISA), mostly used in routine analysis, cannot detect anti-drug antibodies (ADA) in immune...