Abstract
SATB2 is a nuclear protein that plays a critical role in osteoblast lineage commitment. Diagnosing extra skeletal osteosarcomas at rare sites can be quite challenging as it might mimic hyalinized stroma. The utility of SATB2 expression in osteosarcomas and other bone and soft tissue tumours is an useful adjunct to histopathology in diagnosing these rare lesions. A 69 year old male, presented with scrotal swelling since 8 months. He underwent left sided orchidectomy because of the clinical suspicion of malignancy. Macroscopy revealed a solid mass in the para testicular tissue with no involvement of the testicular tissue. Cut surface is whitish, firm and homogenous. Microscopy showed malignant soft tissue tumor with areas showing osteoid differentiation and SAT B2 helped in confirmation of diagnosis by highlighting the osteoblastic nature of cells. Hence a diagnosis of Primary extra skeletal paratesticular osteosarcomas was made.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
