SAT-310 BECK DEPRESSION INVENTORY AND SF-36 AS SCREENING TOOLS FOR DEPRESSION AND ASSESSMENT OF HEALTH-RELATED QUALITY OF LIFE AMONG CHRONIC KIDNEY DISEASE PATIENTS ON HEMODIALYSIS

Abstract

Depression and Health-Related Quality of Life (HRQoL) are of concern among hemodialysis patients. The aim of the study was to assess the HRQoL, identify the presence of depression among hemodialysis patients in a tertiary government hospital and identify the risk factors that lead to it. A descriptive-analytical study was conducted from June to August 2018. A written and informed consent was secured from dialysis patients of the unit. Beck Depression Inventory (BDI) and SF-36 questionnaires were used to identify the presence of depression and assess the HRQoL, respectively. The correlation between the BDI, Physical Component Scale (PCS) and Mental Component Scale (MCS) of SF-36 and the variables analyzed were determined using the Chi-square Analysis. The association among the BDI, PCS and MCS was determined using the Pearson Correlation. A p-value of < 0.05 is considered statistically significant. The likelihood ratios for the significant associations identified were also analyzed. The prevalence of depression in our study population was 47.7%. This percentage is lower compared to the studies done by Nelson et al. (2009) in India, Jofre et al. (2000) in Spain, Mollaoglu (2004) in Turkey whose studies revealed the presence of depression in 83.5%, 70% and 66% on their study populations respectively. Cultural variation and societal factors may play a role in the development of depression and overall HRQoL among dialysis patients. About 60% had poor HRQoL based on PCS scores but only 33% had poor HRQoL based on MCS scores. This stresses the greater impact on the physical limitations compared to the psychological effect experienced by our dialysis patients due to their disease condition. Fourteen patients (13%) were identified to have depression with poor HRQoL. No significant association was noted between the variables and the presence of depression. Normal BMI, age of less than 60 years, pre-HD SBP of less than 130 mmHg, the presence of three or more co-morbidities and a creatinine level of 300-1000mmol/L were associated with poor HRQoL. Patients on hemodialysis for less than one year were shown to have better quality of life. Similar to previous studies, there is a high prevalence of depression and poor HRQoL among hemodialysis patients in our institution. Normal BMI, age of less than 60 years, pre-HD SBP of less than 130 mmHg, the presence of three or more co-morbidities, creatinine levels of 300-1000 mmol/L and dialysis for more than one year predispose to a poor HRQoL. This warrants regular screening for depression and assessment of HRQoL and subsequent intervention to improve treatment outcome.