Abstract

Both Fibroblast growth factor-23 (FGF-23) and Fetuin-A levels have been implicated in mineral and bone disorder associated with chronic kidney disease (CKD), and several single nucleotide polymorphisms (SNPs) of the Fetuin-A gene have also been associated with Fetuin-A levels. This study aimed to determine the relationship between FGF-23 and Fetuin-A and to determine the role of Fetuin-A SNPs with respect to Fetuin-A levels and markers of bone mineralisation in black South African children.

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