SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome.

Marisol Pérez-Toledo ,Scott Hackett,Margaret Goodall,Carrie R Willcox,Benjamin E Willcox,Max Crispin,Adam F Cunningham,Kavitha Masilamani,Eslam Al‐Abadi,Ashish Chikermane,Eleni Syrimi,Yasunori Watanabe,Joel D Allen,Deepthi Jyothish,Mahboob Salim,Mark T Drayson,Hari Krishnan Kanthimathinathan,Barnaby R Scholefield ,Edith Marcial‐Juárez ,S Welch ,Sian Faustini ,Tonny Veenith ,Adrian Shields ,Sian Jossi ,David C Wraith ,Alex Richter

doi:10.1111/pai.13504

SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome.

Marisol Pérez-Toledo , Scott Hackett + Show 24 more

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https://doi.org/10.1111/pai.13504

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Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology	Publication Date: Apr 18, 2021
Citations: 13	License type: NO-CC CODE

Affiliation: Heartlands Hospital, University of Birmingham, University of Southampton, Birmingham Women’s and Children’s NHS Foundation Trust, Cancer Research UK Clinical Trials Unit, University of Oxford, University Hospitals Birmingham NHS Foundation Trust

#Children's NHS Foundation Trust #Children's NHS Foundation + Show 8 more

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Abstract

There is a low rate of symptomatology associated with SARS-CoV-2 infection in children and a substantially lower risk of death than in adults1 . Nevertheless, in rare cases some children present with features of a multisystem inflammatory syndrome with overlapping features of Kawasaki disease and toxic shock syndrome2,3 .

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