SARS-CoV-2 Seroprevalence before Delta Variant Surge, Chattogram, Bangladesh, March-June 2021.

Taufiqur Rahman Bhuiyan,Mamunur Rashid,Juan Dent Hulse,Ashraful Islam Khan,Ishtiakul Islam Khan,Andrew S Azman,Emily S Gurley,Marjahan Akhtar,Sonia T Hegde,Tahmina Shirin,Zahid Hasan Khan,Taufiqul Islam,Rumana Rashid,Shakeel Ahmed,Firdausi Qadri

doi:10.3201/eid2802.211689

Abstract

Highlights

A March–June 2021 representative serosurvey among Sitakunda subdistrict (Chattogram, Bangladesh) residents found an adjusted prevalence of severe acute respiratory syndrome coronavirus 2 antibodies of 64.1% (95% credible interval 60.0%–68.1%)
The Study We conducted a representative serosurvey to understand the prevalence of total SARS-CoV-2 antibodies in residents of the Sitakunda subdistrict (Chattogram district) of Bangladesh, a region with an urban-torural gradient that includes Chattogram, Bangladesh’s second largest city
We conducted the survey over 2 periods, March 27–April 13 and May 23–June 13, because of a national COVID-19 lockdown (April 14–May 30)

Summary

Introduction

A March–June 2021 representative serosurvey among Sitakunda subdistrict (Chattogram, Bangladesh) residents found an adjusted prevalence of severe acute respiratory syndrome coronavirus 2 antibodies of 64.1% (95% credible interval 60.0%–68.1%). The Study We conducted a representative serosurvey to understand the prevalence of total SARS-CoV-2 antibodies in residents of the Sitakunda subdistrict (Chattogram district) of Bangladesh, a region with an urban-torural gradient that includes Chattogram, Bangladesh’s second largest city. We corrected seroprevalence estimates for imperfect test performance, household clustering, and individual-level covariates (e.g., age) using a Bayesian modeling approach documented elsewhere and stratified results to match the target population [3].

Results

Conclusion