Abstract
BackgroundThere are no published cases of tonic-clonic seizures and posterior bilateral blindness during pregnancy and Severe Acute Respiratory Syndrome (SARS) Coronavirus (COV) 2 (SARS-COV-2) infection. We do not just face new and unknown manifestations, but also how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. Coronavirus Disease 2019 (COVID-19), preeclampsia, eclampsia and posterior reversible leukoencephalopathy share endothelium damage and similar pathophysiology.Case presentationA 35-year-old pregnant woman was admitted for tonic-clonic seizures and SARS-COV-2 infection. She had a normal pregnancy control and no other symptoms before tonic-clonic seizures development. After a Caesarean section (C-section) she developed high blood pressure, and we initiated antihypertensive treatment with labetalol, amlodipine and captopril. Few hours later she developed symptoms of cortical blindness that resolved in 72 h with normal brain computed tomography (CT) angiography.ConclusionThe authors conclude that SARS COV-2 infection could promote brain endothelial damage and facilitate neurological complications during pregnancy.
Highlights
There are no published cases of tonic-clonic seizures and posterior bilateral blindness during pregnancy and Severe Acute Respiratory Syndrome (SARS) Coronavirus (COV) 2 (SARS-COV-2) infection
We do not just face new and unknown manifestations, and how different patient groups are affected by SARS-COV-2 infection, such as pregnant women
That is the reason why we present a case report of a pregnant woman infected with SARSCOV-2 who showed seizures and sudden blindness
Summary
The vast majority of patients affected by SARS-COV-2 infection present flu-like symptoms [1, 2]. Symptoms of extrapulmonary disease could be explained by the damage of the endothelial tissue caused by the virus [7] With this new virus, we do not just face new and unknown manifestations, and how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. We notified the case to the Neurology department who suspected posterior reversible leukoencephalopathy as a primary diagnosis, there was no nuclear magnetic resonance confirmation Because of this suspicion, we began treatment with subcutaneous enoxaparin 40 mg every 24 h. The vision of the patient was recovered progressively during the first 48 h and the day she was moved to a COVID-19 hospitalization area with antithrombotic and antihypertensive treatment She has not any neurological symptoms and normal blood pressure without treatment
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