Abstract
SARS : A Tale of Two Epidemics.
Highlights
Several papers from investigators in Hong Kong and Canada have described the clinical, laboratory and radiological features of the disease [7,8,9]
Multiple cell lines were inoculated and a novel coronavirus was isolated from several patients in several different countries who met the case definition of SARS [13,14]
Cytopathological features were noted on Vero E6 cells inoculated with respiratory specimens, and electron microscopic studies of the supernatant from these cell lines revealed characteristic features of a coronavirus [14]
Summary
Several papers from investigators in Hong Kong and Canada have described the clinical, laboratory and radiological features of the disease [7,8,9]. The extensive pulmonary infiltrates and tissue damage noted in the postmortem lung specimens suggest that cytokines or other factors induced by the viral infection may be responsible for the severe lung disease, rather than the virus itself.
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