Abstract
Sarcopenia and liver cirrhosis: comparison of the European working group on sarcopenia criteria 2010 and 2019
Highlights
The liver is the central organ in nutrient metabolism and has many important metabolic functions [1]
Alcohol was the main cause of liver disease in 57.9% of the patient population followed by non-alcoholic steatohepatitis (25.4%) and viral hepatitis (16.7%). 44.7% had a Child A cirrhosis and the median Model for End-stage Liver Disease (MELD) score was 10.8
We were able to show in patients with liver cirrhosis that with the updated 2019 consensus definition, pre-sarcopenia is significantly less often diagnosed compared to the 2010 definition
Summary
The liver is the central organ in nutrient metabolism and has many important metabolic functions [1]. In patients with chronic liver diseases, these metabolic functions are impaired resulting in a variety of nutritional disorders, such as protein-energy-malnutrition (PEM) or muscle abnormalities [2]. Among a wide variety of muscle abnormalities in patients with liver cirrhosis [3], sarcopenia is described as the most common form [4]. There is no gold standard for the diagnoses of sarcopenia in liver cirrhosis patients. General criteria for the diagnosis of sarcopenia are not universally accepted and several different definitions coexist. The European Working Group on Sarcopenia in Older People (EWGSOP) provided consensus criteria for the diagnosis of sarcopenia using muscle mass, muscle strength and muscle performance as a practical clinical definition [7].
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