Abstract
Malignant transformation of mature cystic teratoma (MCT) is rare. Sarcomatoid carcinoma is a neoplasm comprising malignant mesenchymal cells and a conventional carcinomatous area. Here, we report a case of sarcomatoid carcinoma arising from an MCT in the left ovary of a 45-year-old woman. A unilocular cyst consistent with MCT but a nodule within the cyst was confirmed from the resected ovary. Microscopically, the nodule showed both squamous cell carcinoma and pleomorphic sarcomatous components admixing with each other. Lining epithelial cells at the periphery of the main tumor showed squamous metaplasia. It is important to find a squamous cell component, either benign or malignant, when a sarcomatous component was present in the ovary tumor.
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