Sarcoma de Kaposi de presentación inusual como manifestación del síndrome inflamatorio de reconstitución inmunitaria

Abstract

Highly active antiretroviral therapy (HAART) has dramatically reduced HIV-related morbidity and mortality. The complications of HAART include drug-related toxicities, drug interactions, and immune reconstitution inflammatory syndrome (IRIS). IRIS encompasses a diverse range of pathologic inflammatory manifestations that occur in the days to months after HAART is commenced. Many infectious and noninfectious dermatologic manifestations of IRIS have been described. We report the case of an HIV-infected patient who developed Karposi's sarcoma with atypical presentation as the first manifestation of IRIS.